Insigneo seminar: shape matters – radiomic biomarkers of instability in cerebral aneurysms
Thursday, 21 February, 4:00 pm - 5:00 pm GMT
We are delighted to announce that on Thursday 21 February Prof. Dr. Sven Hirsch from the ZHAW Zurich University of Applied Sciences will be visiting the Insigneo Institute and will give a seminar on the subject of ‘shape matters – radiomic biomarkers of instability in cerebral aneurysms’.
Being a physicist Sven has contributed to the analysis and modeling of the cerebrovascular system in tight interdisciplinary collaboration with clinicians and vessel biologists. His projects are situated at different points on the trajectory from bench to bedside in the domain of digital heath.
Past projects encompass the modeling of tumor growth and angiogenesis, simulation of the TAVI intervention and estimation of wall shear stress incorporating turbulent kinetic energy dissipation.
The work on detecting biomarkers for instability in cerebral aneurysms has become a main focus of his research group. The efforts started with a viscoelastic modeling of thrombus formation as a research tool and continued translationally to bridge between basic research and clinicians needs. In the context of the project AneuX they set out to detect new biomarkers for the cerebral aneurysm disease. They analyze IAs according to shape features by establishing a supervised machine learning pipeline using a comprehensive set of morphological descriptors. Thus they characterize shape phenotype and interrelate it with the disease status.